Other Research Studies

To view summaries of studies that are currently enrolling participants, please click on the states/country names listed below. Additional studies can be viewed at: http://www.clinicaltrials.gov/ct/search?term=vulvar+vestibulitis and http://www.clinicaltrials.gov/ct/search?term=vulvodynia

United States

California

University of California Los Angeles (Los Angeles, CA)
Subject

Participants Needed for a Study on Vestibulodynia (Pain at the opening of the vagina with touch, sexual contact and/or tampon use).

Contact

For more information please contact Eva Gonzales at:
obgynresearch@mednet.ucla.edu
(310) 206-6049

Requirements

If you are a female 18-50 years of age who has had at least 3 continuous months of pain at the vaginal opening with touch, tampon use, and/or sexual contact, you may be eligible to participate in this study. This study is open for enrollment at UCLA Westwood Medical Plaza and will remain open for 4 more years. Study involvement includes 4 study visits over a six month time period. Participants are given free medication, free parking and compensation for their time.

Website

https://sites.duke.edu/updatestudy/

Illinois

University of Illinois at Chicago (Chicago, IL)
Subject

Women suffering from vulvodynia needed for study in Chicago to examine the effects of acupuncture on vulvodynia pain and symptoms.

Contact

To find out if you are eligible or if you want more information, please contact us at:

Monya Meinel
meinemo@uic.edu
312-996-5814

Requirements

We are looking for women suffering from vulvodynia or vulvar pain to participate in a research study looking at whether acupuncture can help manage vulvodynia pain. The study includes 10 acupuncture treatments over 5 weeks, and will be conducted at the University of Illinois at Chicago College of Nursing and other locations in North Chicago and Wilmette. There are no acupuncture points in the genital area. Women who are 18 years of age or older who have vulvodynia pain and are not pregnant may qualify to join the study. If you are interested in joining the study, please contact us to see if you are eligible to participate. Visit our website for more information and study locations.

Website

http://vulvodyniastudy.uic.edu/

New York

New York City (NY)
Subject

Participants are needed for a study on Topical Treatment for Sexual Pain in Postmenopausal Women Not Taking Estrogens or Similar Hormones

Contact

If you are interested in participating or have any questions, please email clinicaltrialpa@gmail.com

Requirements

You may be eligible to participate in this study if you are:

-postmenopausal 70 years or younger
– have a clinical diagnosis of vulvar vaginal atrophy
-have pain during sexual contact
-not taking any estrogens, hormones
-other inclusion criteria may apply

If you qualify, you may receive at no cost:

-a topical botanical study investigational drug or placebo
-study-related care from a local doctor
-compensation for time and travel

Website

https://clinicaltrials.gov/ct2/show/NCT03682601?term=NCT03682601&draw=2&rank=1

New York City (NY)
Subject

Vulvar Vestibular Pain Research Study

Contact

If you are interested in participating you can take this questionnaire to determine your eligibility: https://screen.trialfacts.com/s3/tf246-vestibulodynia-study.
If you have any questions, please email wendymd@gmail.com.

Requirements

You may be eligible to participate in this study if you are a woman aged 35 to 70 years old who is postmenopausal (either naturally or surgically) for at least one year.


Inclusion Criteria:

• Must be interested in engaging in activity that requires contact with the vulvar vestibule.
• Must be experiencing vulvar vestibular pain. Vulvar vestibular pain is defined as experiencing pain in the area surrounding the opening of the vagina.
• Must be able to attend 3 study visits over a 4 week period at the research gynecologist’s office as well as take a follow-up online survey 2 weeks after the study has finished (6 weeks).

Website

https://trialfacts.com/tf246-vestibulodynia-study/

North Carolina

University of North Carolina School of Medicine (Chapel Hill, NC)
Subject

A Necessary Multi-Parametric Evaluation of Vulvodynia

Contact

If you are interested in taking part in this study, please go to the following page http://www.med.unc.edu/ppru/research and click on the “Registry” link at the bottom of the page.

Requirements

Women between the ages of 21 and 75 who have been diagnosed by their doctor with vulvodynia and/or experience pain in the vaginal region upon contact (ie. tampon use, intercourse, or pelvic exam) or without contact, for at least 3 months, may be eligible to participate in this study.

The research study involves undergoing sensory testing, a modified gynecological exam and will require 3 visits to the University of North Carolina. Participants will receive up to $200 for complete participation. The purpose of this study is to get a better understanding of a chronic pain syndrome called vulvodynia, or pain in the vulvar (pelvic) region.

Website

http://www.med.unc.edu/ppru/research/current-research-1/a-necessary-multi-parametric-evaluation-of-vulvodynia

University of North Carolina (Chapel Hill, NC)
Subject

Participants Needed for a Study on Vestibulodynia (Pain at the opening of the vagina with touch, sexual contact and/or tampon use).

Contact

To find out if you are eligible or if you want more information, please contact Debbie Farb at:
debbie.farb@unc.edu
(919) 886 – 3024

Requirements

If you are a female 18-50 years of age who has had at least 3 continuous months of pain at the vaginal opening with touch, tampon use, and/or sexual contact, you may be eligible to participate in this study. This study is open for enrollment at UNC Hospitals, Hillsborough Campus, and will remain open for 4 more years. Study involvement includes 4 study visits over a six month time period. Participants are given free medication, and compensation for their time.

Website

https://sites.duke.edu/updatestudy/

Texas

Texas Tech University Health Sciences Center (Midland, TX)
Subject

A Prospective Longitudinal Data Bank Creation to Study Vaginal Conditions With a Novel Diagnostic Approach

Contact

For more information please contact Jennifer R Hinojosa, RN, by phone 432-335-5113  or email  jennifer.hinojosa@ttuhsc.edu  

Requirements

The purpose of this study is to identify and elucidate the pattern and perhaps role of atypical proteins, cytokines and vaginal microbial flora in the pathogenic mechanisms involved in the development of vulvodynia, recurrent fungal and bacterial vaginosis and preterm labor.


Eligibility
Ages Eligible for Study:  
21 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:  
Female
Accepts Healthy Volunteers:  
Yes


Sampling Method:  
Non-Probability Sample


Study Population
All patients willing to participate, and give informed consent, and Asymptomatic, non-pregnant, healthy women ages 21 to 75 years with no previous history of any chronic or recurrent vulvovaginal condition who attend our clinical offices for their annual well-woman physical examination.
2—Non-pregnant women ages 21 to 75 years being evaluated for any gynecological vulvovaginal condition.
Pregnant women ages 21 to 75 years who are both asymptomatic and healthy Pregnant women ages 21 to 75 who have any gynecological vulvovaginal condition


Criteria
Inclusion Criteria:
All patients willing to participate, and give informed consent, and
Asymptomatic, non-pregnant, healthy women ages 21 to 75 years with no previous history of any chronic or recurrent vulvovaginal condition who attend our clinical offices for their annual well-woman physical examination.
Non-pregnant women ages 21 to 75 years being evaluated for any gynecological vulvovaginal condition.
Pregnant women ages 21 to 75 years who are both asymptomatic and healthy
Pregnant women ages 21 to 75 who have any gynecological vulvovaginal condition
Exclusion Criteria:
Asymptomatic patients ages < 21 or > 75, or symptomatic patients ages < 21 or > 75 years.
Patients diagnosed with cancer or having any medical condition that is not under control including: diabetes mellitus, hypertension, collagen disease, hemoglobinopathy, renal insufficiency, depression, anxiety, psychosis and panic attacks
Patients unable to follow the protocol or unwilling to participate

Website

https://clinicaltrials.gov/ct2/show/NCT01829204?term=vulvodynia&rank=34

Virginia

McLean Center for Complementary and Alternative Medicine (Vienna, VA)
Subject

Effect of Two Acupuncture Protocols on Vulvodynia (Acu/Vul-pain)

Contact

For more information, or if you are interested in participating in this study, please contact Arthur Y Fan, MD (CHN), PhD by phone 703-499-4428 or email ArthurFan@ChineseMedicineDoctor.us

Requirements

You may be eligible to participate in this study if you are a women between the ages of 18 and 45, have been diagnosed with generalized and/or provoked vestibulodynia by an OB/GYN or pain specialist and have a current pain score higher than 4 with tampon insertion and removal, or cotton swab test at the initial screen test. Participants must be able to speak and read either English or Chinese.

This study evaluates acupuncture for the treatment of vulvodynia; specifically, if it reduces vulvar pain, pain duration and pain with intercourse. It also examines how long the effect of acupuncture lasts in women with vulvodynia. One-third of the women will receive acupuncture focused on pudendal nerve distribution area; another one-third of the women will receive acupuncture focused on traditional meridian points; the other one-third of women will receive standard care (without acupuncture). Women who experience a reduction in pain (included in subjective and objective scores) will have their pain monitored once a week for up to 6 weeks to see if the acupuncture effect lasts.

Exclusion Criteria:

1. infectious conditions of the vulva/vagina;
2. inflammatory conditions of the vulva/vagina;
3. neoplastic disorders of the vulva/vagina;
4. neurologic disorders of the vulva/vagina;
5. acute trauma to the genitals;
6. iatrogenic conditions of the genitals
7. hormonal deficiencies
8. co-morbid pelvic pain conditions (to avoid confounding pain outcomes) such as pelvic inflammatory disease and documented history of endometriosis
9. menopause
10. patients who have active migraine headaches, temporomandibular joint disease (TMJ), irritable bowel syndrome (IBS), interstitial cystitis, painful bladder syndrome, or fibromyalgia, in past 6 month.

Website

https://clinicaltrials.gov/ct2/show/study/NCT03481621#contacts

Abroad

Netherlands

University of Amsterdam (Amsterdam, The Netherlands)
Subject

Anthropological Research Project on Chronic Vulvar Pain

Contact

For further information or for any questions, please email maya.lane@hotmail.com

Requirements

Participants are needed for an anthropological research project at the University of Amsterdam on chronic vulvar pain. The project is open to individuals who live in the Netherlands. A formal diagnosis of vulvodynia or vestibulodynia is not required. Anyone who has experienced vulvodynia, vestibulodynia, pain during sex, itching, soreness, etc. is welcome. The project will use qualitative interviews that focus on personal experiences and stories of chronic vulvar pain, therefore, any information is valid and useful. Of particular interest are individuals who have tried both medical and alternative treatments to manage their vulvar pain. The main research question that will be addressed is: How do people understand and experience vulvodynia? Participant interviews will be recorded, however, all data will be anonymized and confidential.